Stem Cell Therapy for Chronic Tendonitis: Targeting the Root Cause
Tendonitis
Rejuva Cell Medical Group
Moving Beyond Band-Aid Solutions for Tendon Pain
Tendonitis is one of the most common soft tissue injuries—and one of the most frustrating to treat. While rest, ice, physical therapy, and anti-inflammatory drugs may help short term, many patients experience persistent, recurring pain that affects work, sport, and daily life.
Chronic tendonitis often signals cellular degeneration, not just inflammation.
That’s where stem cell therapy offers a breakthrough. Instead of masking the pain, regenerative treatment addresses the root cause—damaged, inflamed, or poorly healing tendon tissue—and helps rebuild it at the cellular level.
What Is Chronic Tendonitis?
Tendonitis refers to inflammation of a tendon, the tissue that connects muscle to bone. In its chronic form, it’s often more than inflammation—it’s tendinosis, where the tendon fibers degenerate and scar.
Common sites:
Elbow (tennis/golfer’s elbow)
Achilles tendon
Patellar tendon (jumper’s knee)
Shoulder (supraspinatus or rotator cuff)
Wrist, hip, or hamstring
Symptoms:
Persistent, localized pain
Stiffness or pain with movement
Swelling or thickening of tendon
Loss of strength or grip
Recurrence after short periods of relief
How Stem Cells Heal Tendon Tissue Naturally
Mesenchymal stem cells (MSCs) work by promoting true regeneration, not just temporary relief. When injected into or around the injured tendon, they create a pro-healing environment that restores tissue structure and function.
Regenerative Actions:
Differentiate into tenocytes, the cells that build tendon fibers
Increase production of type I collagen, restoring tendon strength
Reduce inflammation and cytokine activity
Improve blood flow and angiogenesis in degenerative tendon areas
Enhance tissue flexibility and reduce scarring
“Stem cells don’t just reduce symptoms—they help restore tendon biology.”
How the Treatment Works
Step
Details
Assessment
Imaging (MRI or ultrasound), physical exam, chronicity evaluation
Injection
MSCs injected under ultrasound guidance directly into the tendon sheath or degenerated zone
Procedure Time
~60 minutes, no general anesthesia required
Recovery
Light use for 3–5 days, then guided rehab protocol over weeks
Optional: Exosomes or PRP may be added for enhanced signal amplification.
Who Should Consider Stem Cell Therapy for Tendonitis?
You may be a good fit if you:
Have chronic tendonitis or tendinosis lasting 3+ months
Have not improved with physical therapy or cortisone injections
Want to avoid surgery or repeat procedures
Are active and need faster recovery for work or sport
Have recurring overuse injuries that limit mobility or performance
Evidence from Clinical Research
A 2022 study in Stem Cells International found that MSC therapy resulted in improved tendon structure and pain relief in 84% of patients with chronic Achilles tendinopathy.
Imaging showed greater tendon fiber alignment and vascularization compared to corticosteroid injections.
Long-term follow-ups revealed lower re-injury rates and higher return-to-activity scores.
Healing Story: Karla, 37 — Hairstylist with Elbow Tendonitis
“Years of repetitive work left me with terrible pain in my elbow. I tried everything—braces, ice, even cortisone shots. Nothing lasted. One stem cell injection changed everything. Within weeks, the burning pain faded, and I was back behind the chair—no pills, no downtime.”
Expected Outcomes
Benefit
Timeline
Pain and inflammation reduction
2–3 weeks
Improved grip or range of motion
4–6 weeks
Tendon fiber remodeling (imaging)
3–6 months
Lower risk of re-injury
Ongoing
Return to work or sport
6–8 weeks
Calculate Your Custom Tendon Repair Plan
Use the calculator below to estimate your treatment cost, based on tendon severity, exosome add-ons, and recovery support.